Migraine is one of the most prevalent neurovascular disabling disorders encountered in Shalakya practice. It is characterized by sudden, paroxysmal episodes, typically presenting as severe unilateral headaches. In Ayurvedic literature, migraine is referred to as Ardhavabhedaka, a significant health concern that primarily affects individuals between 30 and 50 years of age. According to the World Health Organization (WHO), migraine ranks as the third most common disease worldwide, with a global prevalence estimated at 14.7%. Chronic migraine affects approximately 2% of the global population, with a female-to-male ratio of 3:1. This disorder is marked by recurrent headaches, which may occur with or without aura, often resulting in chronic and intermittent disability.

There are groups of herbs described in Samhitas. One such group, Aragwadhadi Gana, is mentioned by Acharya Vaghbhat in Ashtanga Hridaya Samhita in 15th chapter of Sutrasthana. This article attempts to elaborate on Aragwadhadi Gana through the application of Yoga Tantrayukti. The literature on the drugs of this group was collected from Ayurvedic classics and relevant research articles were gathered from published sources for reviewing. In the 15th chapter of Sutrasthana in Ashtanga Hridaya Samhita, the Uddeśa part of Yoga Tantrayukti is described. The Nirdeśa part of Yoga Tantrayukti is observed while exploring the Chikitsasthan, where details regarding the Aragwadhadi Gana are provided, such as the conditions in which it is used, the form in which it should be administered, and the route of administration. Most of the herbs in Aragwadhadi Gana possess Tikta (bitter), Kashaya (astringent), and Katu (pungent) properties. They are indicated in diseases such as Chardi (vomiting), Kushta (skin disorders), Visha (poison), Jwara (fever), Kaphaja Vikara (vitiation of Kapha Dosha), Kandu (pruritis), Prameha (urinary disorders), and Dushta Vrana (non-healing/ bad wound). By application of Yoga Tantrayukti it is observed that many forms of medication and different routes of administration are mentioned in Chikitsasthana and Uttarasthana, which are not clearly mentioned in Shodhanadi Gana Sangraha Adhyay. Furthermore, the use of Aragwadhadi Gana is observed in diseases which are not mentioned in the verses of Gana. Application of Yoga Tantrayukti has proven beneficial in elaborating the concept of Aragwadhadi Gana.

This study evaluates the physicochemical properties and toxicity levels of Shuddha and Ashuddha Bhallataka (Semicarpus anacardium). Three samples were analyzed: a sample with unpurified Bhallataka (Ashuddha), sample 1 with purified Bhallataka, and sample 2 with purified Bhallataka prepared using Ishtika Churna. Various analytical parameters, including loss on drying, total ash value, pH, and phenolic content, were assessed. Thin layer chromatography (TLC) was used to compare the chemical composition of the samples. The results showed significant differences in physicochemical properties and phenolic content between the purified and unpurified samples. The study highlights the importance of proper purification techniques in minimizing the toxic effects of Bhallataka and ensuring safe use in medicinal formulations.

Ashmari is one of the global ailments of the Mutravahasrotas. The symptomatology of Ashmari resembles the clinical features of urolithiasis mentioned in contemporary medical science. Symptoms such as Basti Pida (discomfort and pain in the bladder), Mutrakriccha (difficulty in micturition), Bastishira Vedana (pain in urethra), Mushka Vedana (pain in testicles) and Shepha Vedana1 (pain in the penis) have been described in Ayurvedic classical texts. The present study describes the case of a 33-year-old male patient who visited our OPD with complaints of pain in the lower abdomen, associated with burning and painful micturition. He came along with USG reports showing a calculus measuring about 4.4 mm in the mid-pole of the right kidney and 3.5 mm in the lower pole of the left kidney. The patient was treated with Varunadi Kashaya, Gokshuradi Guggulu, and Stonvil capsules for 15 days, after which symptomatic relief and a reduction in the size of the stones were observed.

Tamaka Shwasa is a very common disease in India. It is a type of Shwasa Roga described in Ayurveda, commonly correlated with bronchial asthma. It is a chronic and recurrent condition characterized by dyspnea, wheezing, cough, and chest tightness. The pathogenesis primarily involves the vitiation of Kapha and Vata Doshas and Pranavaha Srotasa. Among the various treatment modalities mentioned in Ayurveda for Shwasa Roga, Vamana Karma (therapeutic emesis) plays a vital role in the management of Tamaka Shwasa, especially during the acute Kapha-dominant phase. A clinical intervention was conducted involving patients diagnosed with Tamaka Shwasa. After proper Purvakarma (pre-operative procedure), Vamana Karma was administered using classical guidelines. The efficacy was assessed based on symptoms before and after treatment. Patients showed significant improvement in respiratory symptoms following Vamana Karma. A decreased dose dependency was also observed. The results suggest that Vamana Karma effectively reduces Kapha accumulation, restores Doshas balance and improves respiratory function in Tamaka Shwasa.

Janu Sandhigata Vata is a type Vata Vyadhi that occurs most prominently in elderly individuals. Two major types of Samprapti of Janu Sandhigata Vata are Dhatu-Kshayajana and Margavarodhajanya. Sandhigat Vata can be correlated with osteoarthritis described in modern medicine. The prevalence of knee osteoarthritisis is about 10% in men and 13% in women. Although many modern medications are available, they have limited success and may cause side effects. In Ayurveda many internal medications and Panchakarma therapies—especially Basti—are available, which are highly beneficial. Basti predominantly works as Vataghna and provides long-lasting effects by producing Sampraptibhang Chikitsa. The present case discusses a 68-year-old male patient diagnosed with Kshayajanya Janu Sandhigata Vata. In the Samhitas, Janu Sandhigata Vata is explained in the Vatavyadhi Chikitsa Adhyaya. In this case, all Hetu, Rupa, Upashay-Anupashay were consistent with Kshayjanya Janu Sandhigata Vata. Therefore, among Niruha and Sneha Basti, in this case Basti with Tila Taila was chosen. Pachana was administered to the patient, followed by Tila Taila Matra Basti, 60 mL, given for 8 days after taking food (Bhojana Paschat). Assessment of criteria was done on the 0th, 8th, and 15th days of Matra Basti with Tila Taila and daily followup of Basti Pratyagamana was recorded. Shamana Chikitsa was given along with the Panchakarma Chikitsa which provided an additional effect in Vyadhi Shamana. This treatment showed marked improvement in the symptoms of Vyadhi, and the condition was treated successfully. Due to its Snigdha and Ushna Guna, Tila Taila helps reduce the Ruksha, Sheeta, and Laghu Guna of vitiated Vata. Symptomatic relief was observed from the 3rd day of treatment. In this case study, 8 days of Tila Taila Matra Basti along with Shamana Chikitsa showed significant improvement in Janu Sandhigata Vata Vyadhi.

Indralupta is a condition characterized by patches of hair loss spread on the scalp and body. According to modern medical science, it can be correlated with alopecia areata. This case report presents the effectiveness of Shamana (treatment that pacifies aggravated Doshas) along with Panchakarma procedures in a patient with Indralupta. A 10-year-old male patient presented with a patch of hair loss over the scalp for the past 2 months. For treatment, Shamana Chikitsa along with Panchakarma procedures such as Nasya, Shiropichu, Nabhipuran, and Shirolep were advised. Hair regrowth began on the affected patch of the scalp after starting initiation of treatment. In this case, regrowth of hair from hair follicles was evident within 15 days of treatment. The findings of this study suggest that Shamana treatment combined with Panchakarma procedures can provide significant relief in Indralupta.